The focus of my lab is in the areas of drug delivery, nanotechnology and RNA therapeutics. We study the role of small nucleic acids, such as mi/siRNAs, in combination with chemotherapeutics for the treatment of cancer. We utilize nanotechnology and novel drug delivery methods as tools to deliver active compounds and target them to different cells. Our research expands beyond cancer, such as inflammation, brain delivery and other. We use medicinal chemistry and biotechnology to study and develop polymers to serve as carriers for controlled delivery of small and large molecules, proteins, and RNAs.
2017-Present: Adjunct Faculty
Biomedical Engineering, LA Tech, Ruston.
2016-Present: Assistant Professor Pharmaceutics (tenure-track)
Department of Basic Pharmaceutical Sciences
School of Pharmacy, University of Louisiana at Monroe
2014-2016: Post-Doctoral Associate
NCI Center of Cancer Nanotechnology Excellence, Department of Pharmaceutical Sciences
School of Pharmacy, Northeastern University
2010-2014: Research Scientist/Post-Doctoral Associate
Division of Cancer Prevention with Dr. Basil Rigas, MD, MSc
Department of Medicine, Stony Brook University, SUNY
2005-2009: Doctor of Philosophy, Pharmaceutical technology, drug delivery and nanotechnology, Laboratory of Pharmaceutical Technology, Department of Pharmacy, University of Patras
2000-2005: Bachelor of Science in Chemical Engineering, School of Chemical Engineering, National Technical University of Athens
A. K. M. Nawshad Hossian
Nawshad is a PhD student in our lab. His research focus is the synthesis and characterization of a novel drug carrier for the delivery of miRNAs to inhibit the growth of lung cancer. Nawshad uses analytical techniques, such as NMR, Mass spectrometry and HPLC, to synthesize and characterize new polymeric structures. He is familiarized with drug formulation and characterization techniques, including imaging, DLS and electron microscopy. Finally, Nawshad uses in-vitro methods and techniques to analyze transfection, gene expression and regulation, using qPCR, Western blot, RNA-seq, gel electrophoresis, and flow cytometry.
Nawshad has a Masters in Pharmacy, from the State University of Bangladesh, where he also obtained his Bachelors from the School of Pharmacy. He worked for approximately 4 years in the pharmaceutical company named Radiant Pharmaceuticals Ltd. in the Quality Assurance Department and has been the recipient of Bangladesh-Sweden trust fund travel grant award.
Sagun is a PhD student in our lab. Her research focus is on the development of novel drug delivery approaches, based on nanotechnology, for the delivery of active compounds, such as nucleic acids. Sagun uses DLS, NMR, Mass spectrometry, HPLC and other analytical techniques for the development of novel molecules for drug delivery and active targeting, while utilizing biological techniques, such as qPCR, Western Blot and Flow Cytometry to evaluate gene expression and the inhibitory activity of shRNAs, siRNAs, and miRNAs.
She completed her undergraduate Bachelor's studies on Pharmacy from Kathmandu University, Nepal. Having a deep-rooted interest in laboratory settings and research, she worked as a Research and Development analyst at Time Pharmaceuticals, Nepal. She is interested in drug delivery systems and more specific to work on cancer therapy, based on nanotechnology. Sagun aspires to enhance her professional career and contribute to the research of medical and pharmaceutical sciences.
Johnitie Thanh Le
Previous Lab Members
April M Stelly
Lac Thi Ngyuen
Dalena Thi Ngyuen
David Barron Anderson
Annalise Elizabeth Labatut
Dylan C Guillaume