PUBLICATIONS

  • Hossian A, Sajib M, Tullar P, Mikelis C, Karen Briski, Mattheolabakis G, Analysis of combinatorial miR treatments to regulate Cell Cycle and Angiogenesis, Accepted – JoVE, 2019; in press (invited publication)

  • Hossian A, Sajib M, Tullar P, Mikelis C, Mattheolabakis G, Multipronged activity of combinatorial miR-143 and miR-506 inhibits Lung Cancer cell cycle progression and angiogenesis in vitro, Scientific Reports, 2018, doi: 10.1038/s41598-018-28872-2

  • Labatut A, Mattheolabakis G, Non-Viral Based miR Delivery and Recent Developments, European Journal of Pharmaceutics and Biopharmaceutics, 2018, 10.1016/j.ejpb.2018.04.018

  • Guorgui J., Wang R., Mattheolabakis G., Mackenzie G., Curcumin formulated in solid lipid nanoparticles has enhanced efficacy in Hodgkin’s lymphoma in mice, Archives of Biochemistry and Biophysics, 2018, doi: 10.1016/j.abb.2018.04.012

  • Mattheolabakis  G., Wang R., Rigas B. and Mackenzie G.G., Phospho-valproic acid inhibits pancreatic cancer growth in mice: enhanced efficacy by its formulation in poly-(L)-lactic acid-poly(ethylene glycol) nanoparticles, International Journal Of Oncology, 2017;doi: 10.3892/ijo.2017.4103. PubMed PMID: 28849098

  • Mattheolabakis G, Ling D, Ahmad G, Amiji M., Enhanced Anti-Tumor Efficacy of Lipid-Modified Platinum Derivatives in Combination with Survivin Silencing siRNA in Resistant Non-Small Cell Lung Cancer, Pharm Res. 2016 Aug 15
     

  • Berman M, Mattheolabakis G, Suresh M, Amiji M, Reversing epigenetic mechanisms of drug resistance in solid tumors using targeted microRNA delivery, Expert Opin Drug Deliv. 2016 Apr 29:1-12
     

  • Ryo Hotta, Lily Cheng, Hannah K. Graham, Nandor Nagy, Jaime Belkind-Gerson, George Mattheolabakis, Mansoor M. Amiji, and Allan M. Goldstein, Delivery of enteric neural progenitors with 5-HT4 agonist-loaded nanoparticles and thermosensitive hydrogel enhances cell proliferation and differentiation following transplantation in vivo, Biomaterials, 2016 May; 88:1-11
     

  • Salzano G, Costa DF, Sarisozen C, Luther E, Mattheolabakis G, Dhargalkar PP, Torchilin VP, Mixed Nanosized Polymeric Micelles as Promoter of Doxorubicin and miRNA-34a Co-Delivery Triggered by Dual Stimuli in Tumor Tissue., Small. 2016 Jul 19. doi: 10.1002/smll.201600925
     

  • Amit Singh, Jing Xu, George Mattheolabakis, and Mansoor Amiji, Redox-Responsive EGFR-Targeted Gelatin Nanoparticles for Combination wt-p53 Plasmid DNA and Gemcitabine Treatment in Pancreatic Cancer Cells, Nanomedicine. 2015 Dec 3. pii: S1549-9634(15)00217-8. doi: 10.1016/j.nano.2015.11.010
     

  • Lara Milane, Amit Singh, George Mattheolabakis, Megha Suresh, and Mansoor M. Amiji, Exosome Mediated Communication within the tumor microenvironment, J Control Release. 2015 Jul 1. pii: S0168-3659(15)30001-8. doi: 10.1016/j.jconrel.2015.06.029.
     

  • George Mattheolabakis, Lara Milane, Amit Singh, Mansoor Amiji, Hyaluronic Acid Targeting of CD44 for Cancer Therapy: From Receptor Biology to Nanomedicine, (Invited review for Special Issue in honor of dr. Langer). J Drug Target, 2015; 23(7–8): 605–618
     

  • Huyen Tran, George Mattheolabakis, Hibah Aldawsari, and Mansoor Amiji. Exosomes as Nanocarriers for Immunotherapy of Cancer and Inflammatory diseases, Clin Immunol. 2015 Apr 2, pii: S1521-6616(15)00124-2. doi: 10.1016/j.clim.2015.03.021
     

  • George Mattheolabakis, Ioannis Papayannis, Jennifer Yang, Brandon M. Vaeth, Ruixue Wang, Nengtai Ouyang, Basil Rigas and Gerardo G. Mackenzie, Phospho-aspirin (MDC-22) prevents pancreatic carcinogenesis in mice, Cancer Prev Res(Phila). 2016 Jul; 9(7):624-34
     

  • Lauren E. Bartels, George Mattheolabakis, Joseph F. LaComb, Brandon M Vaeth1, Jizu Zhi, Basil Rigas and Gerardo G. Mackenzie, The novel agent phospho-glycerol-ibuprofen-amide (MDC-330) inhibits glioblastoma growth in mice: An effect mediated by cyclin D1, Carcinogenesis. 2016 Apr; 37(4):420-9
     

  • Wong, Chi; Cheng, Ka Wing; Papayannis, Ioannis; George Mattheolabakis; Huang, Liqun; Xie, Gang; Ouyang, Nengtai; Rigas, Basil, Phospho-NSAIDs have enhanced efficacy in mice lacking plasma carboxylesterase: Implications for their clinical pharmacology, Pharm Res. 2014 Nov 13
     

  • George Mattheolabakis, Chi C Wong, Yu Sun, Carol A Amella, Robert Richards, Panayiotis P. Constantinides, Basil Rigas, Pegylation improves the pharmacokinetics and bioavailability of small-molecule drugs hydrolysable by esterases: A study of phospho-ibuprofen, Journal of Pharmacology and Experimental Therapeutics, jpet.114.217208; published ahead of print July 21, 2014, doi:10.1124/jpet.114.217208
     

  • Ka Wing Cheng, Ting Nie, Nengtai Ouyanga, Ninche Alston, Chi C. Wong, George Mattheolabakis, Ioannis Papayannis, Liqun Huang, Basil Rigas. A novel ibuprofen derivative with anti-lung cancer properties: Synthesis, formulation, pharmacokinetic and efficacy studies, International Journal of Pharmaceutics, Oct 2014, doi:10.1016/j.ijpharm.2014.10.019
     

  • Gerardo G. Mackenzie, Liqun Huang, Ninche Alston, Nengtai Ouyang, Kvetoslava Vrankova, George Mattheolabakis, Panayiotis P. Constantinides, Basil Rigas, Targeting Mitochondrial STAT3 with the Novel Phospho-Valproic Acid (MDC-1112) Inhibits Pancreatic Cancer Growth in Mice, PLOS ONE, May 2013, Volume 8, Issue 5, e61532
     

  • Ka-Wing Cheng , Chi C. Wong , George Mattheolabakis , Gang Xie, Liqun Huang and Basil Rigas, Curcumin enhances the lung cancer chemopreventive efficacy of phospho-sulindac by improving its pharmacokinetics, Int J Oncol. 2013 Sep;43(3):895-902. doi: 10.3892/ijo.2013.1995. Epub 2013 Jun 27
     

  • George Mattheolabakis, Gerardo G. Mackenzie, Liqun Huang, Nengtai Ouyang, Ka Wing Cheng, Basil Rigas, Topically applied phospho-sulindac hydrogel is efficacious and safe in the treatment of experimental arthritis in rats, Pharmaceutical Research, March 2013, DOI 10.1007/s11095-012-0953-8
     

  • George Mattheolabakis, Basil Rigas and Panayiotis P. Constantinides, Nanodelivery Strategies in Cancer Chemotherapy: Biological Rationale and Pharmaceutical Perspectives, Nanomedicine, 2012 Oct; 7(10):1577-90
     

  • George E. Magoulas, Thomas Garnelis, Constantinos M. Athanassopoulos, Dionissios Papaioannou, George Mattheolabakis, Konstantinos Avgoustakis, Dimitra Hadjipavlou-Litinac, Synthesis and antioxidative/anti-inflammatory activity of novel fullerene–polyamine conjugates, Tetrahedron, 68, 35, 2 September 2012, 7041–7049
     

  • Ka Wing Cheng, George Mattheolabakis, C. C. Wong, Nengtai Ouyang, Liqun Huang, Panayiotis P. Constantinides and Basil Rigas, Topical phospho-sulindac (OXT-328) is effective in the treatment of non-melanoma skin cancer, International Journal of Oncology, 2012 Jul 27, DOI: 10.3892/ijo.2012.1577
     

  • Spiridoula Kyriakopoulou, George Mattheolabakis, Sofia Papadimitriou, Evangelos Karavas, Dimitrios Bikiaris and Konstantinos Avgoustakis, PPSu-PEG Copolymers and their Application in the Preparation of Cisplatin-loaded Nanoparticles, Current nanoscience, 2011, 7, 4, 503-509
     

  • George Mattheolabakis, Ting Nie, Panayiotis P. Constantinides, Basil Rigas, Sterically stabilized liposomes incorporating the novel anticancer agent phospho-ibuprofen (MDC-917): Preparation, characterization and in vitro/in vivo evaluation, Pharmaceutical Research, 2011, DOI: 10.1007/s11095-011-0619-y
     

  • Zacharoula Iatridi, George Mattheolabakis, Konstantinos Avgoustakis, and Constantinos Tsitsilianisa, Self-assembly and drug delivery studies of pH/thermo-sensitive polyampholytic (A-co-B)-b-C-b-(A-co-B) segmented terpolymers, Soft matter, 2011, 7, 23, 11160-11168
     

  • Alexandros A. Vassiliou, Sofia A. Papadimitriou, Dimitrios N. Bikiaris, George Mattheolabakis, Konstantinos Avgoustakis, Facile synthesis of polyester-PEG triblock copolymers and preparation of amphiphilic nanoparticles as drug carriers, Journal of Controlled Release, 148-3,  2010,  388-395
     

  • Bakandritsos A., George Mattheolabakis, Chatzikyriakos G., Szabo T., Tzitzios V., Kouzoudis D., Couris S., Konstantinos Avgoustakis, Doxorubicin Nanocarriers Based on Magnetic Colloids with a Bio-polyelectrolyte Corona and High Non-linear Optical Response: Synthesis, Characterization, and Properties, Advanced Functional Materials, 2011, 21, 8, 1465-1475
     

  • Blatsios G., Tzimas A., George Mattheolabakis, Panagi Z., Avgoustakis K., Gartaganis S., Development of biodegradable controlled release sclera systems of Triamcinolone acetonide, Current Eye Research, 2010, 35, 10,  916-924.
     

  • Bakandritsos A., George Mattheolabakis, Zboril R.,Bouropoulos N., Tucek J., Fatouros D., Avgoustakis K., Preparation, stability and cytocompatibility of magnetic/PLA-PEG hybrids, Nanoscale, 2010, 2, 564–572
     

  • George Mattheolabakis, Lagoumintzis G., Panagi Z.,Papadimitriou E., Partidos C. D., Avgoustakis K., Transcutaneous Delivery of a Nanoencapsulated Antigen: Induction of Immune Responses, Intern. J. of Pharm. 385, 2010, 187–193
     

  • George Mattheolabakis, Taoufik E., Haralambous S., Roberts M. L., Avgoustakis K., In vivo investigation of tolerance and antitumor activity of cisplatin-loaded PLGA-mPEG nanoparticles, E. J. Pharm. Biopharm., 2009, 71, 190–195
     

  • Gryparis, E. C., George Mattheolabakis, Bikiaris, D. and Avgoustakis, K. Effect of Conditions of Preparation on the Size and Encapsulation Properties of PLGA-mPEG Nanoparticles of Cisplatin, Drug Delivery, 2007, 14, 371–380